Why are large plastic shells preferred, especially those made through thermoforming?
The two major concerns regarding appearance that contemporary people have are one being a sagging face and the other being baldness.
Polylactic acid (PLA), a family of biodegradable materials derived from nature and fully metabolizable by the human body, is gradually expanding its market reach from high-end applications to a broader range, thanks to its profound scientific principles and outstanding clinical performance. It demonstrates great potential as a pillar material for the next generation of regenerative medicine.
The core value of medical aesthetic regenerative materials goes far beyond simple "filling". It lies in precisely activating the body's own repair and regeneration capabilities. The main ingredient of the "youthful skin injection" is poly-L-lactic acid (PLLA). Its core mechanism of action is that after being injected into the skin, it gradually degrades, gently activating the vitality of fibroblasts and stimulating the body's own collagen production, achieving volumetric filling from the inside out and improvement of skin texture. Therefore, it has firmly established itself as the main player in the field of facial regeneration and anti-aging.
Recently, the patent titled "Application of Poly-Lactic Acid and Its Derivatives Combined with Drugs in Promoting Hair Growth" disclosed by Changchun Shengbo Ma Biomedical Materials Co., Ltd. has expanded the application scope of PLLA from anti-aging of the face to a brand-new scenario of hair loss prevention and hair growth promotion.
This study defined the molecular weight range of polylactic acid and its copolymers as 400 Da to 300 kDa. Through experiments, it was proved that the experimental group containing polylactic acid had a promoting effect on the growth of mice hair, and the hair growth was rapid. This invention provides a new application of polylactic acid in promoting hair growth, and the active ingredient of polylactic acid is safe and has low toxic side effects. It has broad application prospects in the fields of preventive, nursing, and therapeutic drugs, cosmetics, care products, and beauty products for treating rare hair loss, promoting hair health and growth.
This patent specifically compared the effects of using PLLA microspheres alone with those of combining them with traditional hair loss medications such as minoxidil. The final conclusion clearly stated that the combined treatment group not only increased the hair growth rate of androgenetic alopecia mice, but also significantly increased the number of hair follicles in the growth phase, proving the effectiveness of this combined administration method.
In simple terms, PLLA not only can improve the growth environment of hair follicles on its own, but also can work in conjunction with traditional anti-hair loss drugs to enhance their efficacy.
In fact, the application of polylactic acid materials in the field of hair loss prevention has long been a leading research topic at the international level. In January this year, researchers from Yonsei University in South Korea published a clinical study in the "JPRAS Open" journal, evaluating the clinical improvement of 20 patients with androgenetic alopecia and telogen effluvium after receiving polylactic acid scalp injections (partially combined with microneedle therapy).
After 12 weeks of treatment, evaluated by two independent physicians, 90% of the patients showed "improved or better" results in hair loss. The average GAIS score reached 3.3 ± 0.6, and this improvement persisted stably during the 24-week follow-up. The self-assessment results of the patients were highly consistent with the physician evaluations, and the recognition rate was extremely high.
In terms of safety, no serious adverse events occurred throughout the process. Only mild, transient rashes were observed, and there were no delayed nodules, infections, or other issues.
This study also, for the first time at the human level, verified the feasibility of using polylactic acid materials to improve hair quality by enhancing blood supply around hair follicles and regulating the scalp microenvironment. This laid a crucial foundation for its subsequent clinical application.
